API Impurity
| CAS Number | 104987-11-3 |
| Formula | C₄₄H₆₉NO₁₂ |
| Molecular Weight | 804.02 g/mol |
| Purity | ≥98–99% |
| Storage | Store at 2–8 °C; protect from light and moisture |
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis that inhibits calcineurin and T-cell activation.
Used as an API in organ transplantation to prevent rejection and in topical formulations for inflammatory skin diseases.
Tested by HPLC (assay and impurities), MS, NMR, optical rotation, and pharmacopoeial methods (USP/EP).
